Method: Shotgun metagenomic sequencing (CLIA 21D2062464); not cleared or approved by the FDA. Results reflect relative microbial abundance for wellness education purposes. Not intended to diagnose or treat disease and not a substitute for clinical consultation. Microbial associations are based on emerging scientific research and may change over time.
A derived biomarker is a value that is calculated from other directly measured biomarkers rather than being measured directly in the lab.
Key benefits of Proteobacteria testing
- Gram-negative bacteria phylum tracking
- gut dysbiosis sentinel phylum monitoring
What is Proteobacteria?
Proteobacteria is a phylum containing many gram-negative bacteria - including E. coli, Salmonella, Helicobacter, Campylobacter, and Klebsiella. In a healthy gut, Proteobacteria is typically a minor phylum. Elevated relative abundance is a recognized marker of gut dysbiosis. Detected by shotgun sequencing.
Why is Proteobacteria important?
Elevated Proteobacteria is consistently observed in gut dysbiosis contexts, inflammatory conditions, and antibiotic-disrupted microbiomes. It serves as a broad sentinel for gut ecosystem imbalance. Its abundance should be interpreted alongside the specific pathogenic species tracked in this panel.
What insights will I get?
Your Proteobacteria level indicates the relative presence of this gram-negative phylum. Elevated Proteobacteria alongside reduced beneficial microbe levels and low diversity may suggest meaningful microbiome dysbiosis worth addressing.
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