Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
A derived biomarker is a value that is calculated from other directly measured biomarkers rather than being measured directly in the lab.
Key benefits of Mercury (Hg) testing
- Mercury exposure tracking
- fish consumption and dental amalgam assessment
- neurotoxic metal monitoring
What is Mercury (Hg)?
Mercury exists in three forms: elemental (from dental amalgams and industrial settings), inorganic (from environmental sources), and organic (methylmercury, primarily from large predatory fish). Urinary mercury primarily reflects inorganic and elemental exposure; post-chelation may mobilize stored mercury. Measured via ICP-MS.
Why is Mercury (Hg) important?
Mercury is a neurotoxin with well-established effects on the nervous system, kidneys, and immune function. Methylmercury from large predatory fish (tuna, swordfish, shark) is the primary source for most adults. Dental amalgams contribute elemental mercury. Regular fish intake monitoring and possible amalgam assessment are relevant for elevated levels.
What insights will I get?
Your urinary mercury level may indicate elemental mercury from dental amalgams or inorganic mercury from environmental sources. Interpreting total mercury alongside methylmercury speciation requires blood testing. Elevated levels may prompt review of predatory fish intake and dental amalgam status.





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